Key result
Exercise systolic blood pressure of 200-275 mm Hg at moderate workload increased the risk of cardiovascular mortality by 1.39-fold compared to 100-160 mm Hg over 35 years (95% CI 1.00-1.93, p=0.05).
Why the study?
Does high exercise systolic blood pressure at moderate workload predict cardiovascular disease and mortality in healthy, middle-aged men?
Cohort (n=1,999)
Does high exercise systolic blood pressure at moderate workload predict cardiovascular disease and mortality in healthy, middle-aged men?
Relative Risk: 1.39 (95% CI 1–1.93)
p-value: p=0.05
Elevated exercise systolic blood pressure at moderate workload is an independent predictor of cardiovascular disease and mortality over a 35-year follow-up in healthy middle-aged men.
No takes yet. Share an insight, caveat, or question.
May refine long-term CV risk stratification; leaves open whether targeting moderate-workload hypertension improves outcomes.
Mariampillai et al. (2017) conducted a cohort in Healthy (n=1,999). Exercise systolic blood pressure at moderate workload (SBP100W) vs. Lowest quartile of exercise SBP (100-160 mm Hg) was evaluated on Cardiovascular mortality (1.39-fold increased risk, 95% CI 1.00-1.93, p=0.05). Exercise systolic blood pressure of 200-275 mm Hg at moderate workload increased the risk of cardiovascular mortality by 1.39-fold compared to 100-160 mm Hg over 35 years (95% CI 1.00-1.93, p=0.05).