Key result
Poincaré analysis of overnight arterial oxygen saturation signals achieved 90.9% sensitivity and 84.0% specificity for the diagnosis of sleep apnea hypopnea syndrome.
Why the study?
Does Poincaré analysis of overnight arterial oxygen saturation signals accurately diagnose sleep apnea hypopnea syndrome?
Observational (n=117)
Does Poincaré analysis of overnight arterial oxygen saturation signals accurately diagnose sleep apnea hypopnea syndrome?
Poincaré analysis of overnight pulse oximetry signals provides high sensitivity and specificity for diagnosing sleep apnea, potentially reducing the need for full polysomnography.
The analysis of oxygen desaturations is a basic variable in polysomnographic studies for the diagnosis of sleep apnea. Several algorithms operating in the time domain already exist for sleep apnea detection via pulse oximetry, but in a disadvantageous way--they achieve either a high sensitivity or a high specificity. The aim of this study was to assess whether an alternative analysis of arterial oxygen saturation (SaO2) signals from overnight pulse oximetry could yield essential information on the diagnosis of sleep apnea hypopnea syndrome (SAHS). SaO2 signals from 117 subjects were analyzed. The population was divided into a learning dataset (70 patients) and a test set (47 patients). The learning set was used for tuning thresholds among the applied Poincaré quantitative descriptors. Results showed that the presence of apnea events in SAHS patients caused an increase in the SD1 Poincaré parameter. This conclusion was assessed prospectively using the test dataset. 90.9% sensitivity and 84.0% specificity were obtained in the test group. We conclude that Poincaré analysis could be useful in the study of SAHS, contributing to reduce the demand for polysomnographic studies in SAHS screening.
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Morillo et al. (2009) conducted an observational in Sleep apnea hypopnea syndrome (SAHS) (n=117). Poincaré analysis of arterial oxygen saturation (SaO2) signals was evaluated on Diagnosis of sleep apnea hypopnea syndrome (SAHS). Poincaré analysis of overnight arterial oxygen saturation signals achieved 90.9% sensitivity and 84.0% specificity for the diagnosis of sleep apnea hypopnea syndrome.