Key result
Ivabradine may reduce BP and protect target organs in high-HR hypertension via improved endothelial function.
Why the study?
Does ivabradine reduce blood pressure in patients with hypertension and elevated heart rate?
Does ivabradine reduce blood pressure in patients with hypertension and elevated heart rate?
Ivabradine may have blood pressure-lowering properties via pleiotropic mechanisms, suggesting a potential role in treating hypertensive patients with elevated heart rate.
May warrant consideration in select cases with elevated heart rate; leaves open confirmation via randomized trials before practice change.
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Šimko et al. (2021) conducted a review in Hypertension and elevated heart rate. Ivabradine was evaluated. Ivabradine may reduce blood pressure and provide target organ protection in hypertensive patients with elevated heart rate through pleiotropic mechanisms including improved endothelial function.
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