Population
Yeast cells and yeast and mammalian in vitro translation systems
Design
Preclinical
Authors
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May enable antiviral strategies targeting -1 frameshifting; leaves open translation beyond yeast models.
Peptidyl-transferase inhibitors like anisomycin and sparsomycin alter -1 ribosomal frameshifting and may serve as a new class of antiviral agents.
Dinman et al. (1997) studied this question.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: