Change in Level of Physical Activity and Risk of All-Cause Mortality or Reinfarction
Why the study?
Does increasing or maintaining physical activity reduce all-cause mortality or reinfarction in patients who survived a first myocardial infarction?
Population
406 Mexican American and non-Hispanic white women and men who survived a first myocardial infarction
Comparison
Increased physical activity or maintaining an… vs Remaining sedentary
Design
Cohort
Follow-up
7 years
Authors
Discussion
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Member takes
Implication
Supports activity promotion post-MI in minorities; extends prior evidence but observational data leave causality open.
Key Points
- To assess the relationship between changes in physical activity levels and the risks of all-cause mortality and reinfarction in patients surviving a first myocardial infarction.
- Followed 406 Mexican American and non-Hispanic white men and women who survived a first myocardial infarction over a 7-year follow-up period.
- Conducted baseline and annual interviews evaluating physical activity, medical history, and coronary heart disease risk factors.
- Categorized post-MI physical activity trajectory into four groups: sedentary with no change (reference), decreased activity, increased activity, and active with no change.
- Compared to the sedentary group, the relative risk of all-cause death over 7 years was 0.11 (95% CI, 0.03 to 0.46) for increased activity, 0.21 (95% CI, 0.10 to 0.44) for maintaining active behavior, and 0.49 (95% CI, 0.26 to 0.90) for decreased activity.
- The relative risk of recurrent myocardial infarction was 0.22 (95% CI, 0.09 to 0.50) for increased activity, 0.40 (95% CI, 0.24 to 0.66) for maintaining an active lifestyle, and 0.93 (95% CI, 0.59 to 1.42) for decreased activity relative to remaining sedentary.
Structured PICO
Does increasing or maintaining physical activity reduce all-cause mortality or reinfarction in patients who survived a first myocardial infarction?
P
Population
406 Mexican American and non-Hispanic white women and men who survived a first myocardial infarction
I
Intervention
Increased physical activity or maintaining an active lifestyle after a first myocardial infarction
C
Comparator
Remaining sedentary (no change in physical activity)
O
Outcome
All-cause mortality or reinfarctionhard clinical
Increasing or maintaining physical activity after a first myocardial infarction is associated with a significantly reduced risk of all-cause mortality and reinfarction.
Cite This Study
Steffen et al. (2000) studied this question.