Key result
Higher perceived social support links to better HRQoL, partially mediated by physical activity.
Why the study?
Little is known about the associations among perceived social support, physical activity, and health-related quality of life in patients with ischemic heart disease experiencing hopelessness.
Are perceived social support and physical activity associated with health-related quality of life in patients with ischemic heart disease reporting moderate to severe hopelessness?
Cross-Sectional (n=156)
Are perceived social support and physical activity associated with health-related quality of life in patients with ischemic heart disease reporting moderate to severe hopelessness?
Effect estimate: rpartial -0.24 (PSS) and -0.23 (PA)
p-value: p=.005 (PSS) and .003 (PA)
In patients with ischemic heart disease and moderate to severe hopelessness, better perceived social support and physical activity are associated with improved health-related quality of life.
May support addressing social support and activity in hopeless IHD; leaves open whether interventions improve HRQoL.
BACKGROUND: Associations among perceived social support (PSS), physical activity (PA), and health-related quality of life (HRQoL) in individuals with ischemic heart disease (IHD) are well established. However, little is known about these associationsin patients with IHD experiencing hopelessness. OBJECTIVE: The objective of this study is to explore the associations among PSS, PA, and HRQoL in patients with IHD reporting moderate to severe hopelessness. METHODS: Using a cross-sectional design, secondary data were collected from 156 participants enrolled in a randomized controlled trial while hospitalized in the Midwestern United States. Data were collected 2 weeks after hospital discharge, including the Cardiac Rehabilitation Exercise Participation Tool, ENRICHD Social Support Inventory, EuroQol 5-Dimension 5-Level, and a demographic form. Linear models were used to assess associations among the variables, and Macro process mediation was completed to explore potential mediation. RESULTS: Most participants were male, had some college education or higher, and non-Hispanic White. Over half of the sample were married and not employed (eg, disabled, retired). Higher PSS and higher PA were each separately associated with higher HRQoL after adjusting for relevant covariates (PSS: rpartial = -0.24, P = .005; PA: rpartial = -0.23, P = .003). Engagement in PA ( rpartial = -0.19, 95% bootstrap CI, -0.34 to -0.03; P = .02) partially mediated the relationship between PSS and HRQoL ( rpartial = -0.18, 95% bootstrap CI, -0.35 to -0.01; P = .03) showing a 22% partial mediation with indirect effect at -0.05 (95% CI bootstrap, -0.11 to -0.002). CONCLUSION: Even among patients with high perceptions of hopelessness, better perceived social support and more engagement in physical activity are associated with better HRQoL. Longitudinal research in larger and more diverse samples is needed to examine the relationships among PSS, PA, and HRQoL in patients with IHD reporting hopelessness.
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Alotaibi et al. (2025) conducted a cross-sectional in Ischemic heart disease with moderate to severe hopelessness (n=156). Perceived social support and physical activity was evaluated on Health-related quality of life (HRQoL) (rpartial -0.24 (PSS) and -0.23 (PA), p=.005 (PSS) and .003 (PA)). Higher perceived social support and physical activity were associated with better health-related quality of life, with physical activity partially mediating this relationship (indirect effect -0.05).
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