Evaluation of Efficacy and Safety of Radiofrequency Heating With Targeted Ultrasound and Active Cooling Technology for Localized Fat Reduction

BACKGROUND Noninvasive targeted adipose reduction is highly sought after, with many devices using radiofrequency. Without adequate surface cooling, these treatments may not reach optimal depths and superficial burns can result. OBJECTIVE To evaluate fat reduction, safety, and patient satisfaction with a device combining radiofrequency and targeted ultrasound with superficial active cooling which heats localized adipose tissue while protecting the epidermis. MATERIALS AND METHODS Twenty-three subjects with localized fat underwent 4 treatments of radiofrequency with targeted ultrasound and active cooling. Pre- and post-treatment evaluations included photographs and measurements using a caliper and ultrasound. Subjects also completed satisfaction and comfort questionnaires. Data were collected at baseline, after the final session, and 1, 3, and 6 months post-treatment. RESULTS Ultrasound showed a gradual fat thickness reduction: −16.3% at 1 month, and −22.5% at 3 and 6 months ( p < .0005). Caliper measurements confirmed this trend: −28.4% at 1 month, −32.9% at 3 months, and −42.5% at 6 months ( p < .0001). Patient satisfaction was high, with 71.4% reporting improvement at 6 months. CONCLUSION Combining radiofrequency and ultrasound with active cooling effectively reduces adipose tissue while protecting the superficial tissues. Treatments were effective, had a high satisfaction rate, and were shown to be safe.