Cancer-related fatigue in adolescents and young adults

Purpose of review This review aims to provide a comprehensive overview of the prevalence, associated factors, and consequences of cancer-related fatigue (CRF) in adolescents and young adults (AYAs) with cancer, and to examine interventions designed to manage CRF. Recent findings This review included 20 articles, providing an overview of CRF in AYAs. Several studies reported a high prevalence of CRF in AYAs with cancer, both during treatment and in survivorship, associated with reduced quality of life and well-being. Most tested interventions targeted physical activity, including supervised and unsupervised programs, while others focused on self-management in survivorship or involved live music. Summary This review underscored that CRF is prevalent among AYAs with cancer, during treatment and throughout survivorship, with substantial repercussions for overall quality of life. These findings highlight the importance of assessing CRF and implementing supportive interventions to reduce its burden. Future research should advance the development of tailored, developmentally appropriate, and engaging strategies to effectively address CRF in this population.