Simple catalyst system involving boric acid and additives for the direct formation of amides from carboxylic acids and amines

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Key Points

To explore a novel catalyst system using boric acid for the effective conversion of carboxylic acids and amines into amides.
Developed a catalyst system based on boric acid and specific additives.
Conducted amidation reactions between carboxylic acids and amines to assess efficiency.
Analyzed sustainability metrics of the new system compared to traditional methods.
Increased reaction efficiency by a significant margin compared to traditional catalysts.
Demonstrated improved sustainability due to the use of low-cost materials.
Achieved high yields of amides with minimal environmental impact.

Demonstrates improved efficiency of amidation in carboxylic acids and amines, suggesting a sustainable approach.

A new inexpensive catalyst system that uses boric acid and additives increases the efficiency and sustainability of direct amidation reactions.

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Boisvert et al. (2026) studied this question.

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