Answers are grounded in this paper and cite their sources.
Focused review assesses screening methods for colorectal cancer, indicating need for improved sensitivity in emerging tests.
Colorectal cancer (CRC) is a leading cause of cancer-related morbidity and mortality worldwide, with an alarming increase in incidence, particularly in younger individuals. Effective screening is essential for prevention, early detection, and optimal management. Current screening methods include stool-based tests, colonoscopy, and other direct visualization techniques such as flexible sigmoidoscopy, capsule endoscopy, and computed tomography colonography, in addition to emerging blood-based tests. This review provides a concise assessment of diagnostic performance, advantages, and limitations of each method. Colonoscopy and fecal immunochemical tests remain the cornerstone of CRC screening, with the choice ultimately guided by resource availability and patient preferences. While novel blood-based tests offer promises for increasing screening uptake, they require further refinement to enhance sensitivity for precancerous lesions.
No takes yet. Share an insight, caveat, or question.
Majid Alsahafi (2025) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: