Formulation and Evaluation of a Dualfunctional Nanoemulsion Loaded With Green Tea Extract and Vitamin E for Enhanced Topical Cosmeceutical Applications

In this context, this study aims at formulating and characterizing a dual active nanoemulsioncontaining both vitamin E and green tea extract in order to optimize topical cosmeceuticalformulation. Advanced delivery systems able to enhance the stability, bioavailability andactivity of natural active principles are increasingly requested due to the growing demand formultifunctional cosmetic products. While vitamin E functions as a lipophilic antioxidant thatprotects against oxidative damage and enhances skin barrier capacities, green tea extract, whichis rich in polyphenolic compounds, exhibits potent antioxidant and anti-inflammatory actions.In this study, a high-energy emulsification technique was used to generate a nanoemulsionsystem with suitable oils, surfactants, and co-surfactants. preformulation research, whichincluded FTIR spectroscopy compatibility assessments and solubility tests, were carried out toconfirm the stability of the active components. Physiochemical analysis, zeta potential, pH,viscosity, invitro release analysis, and drug content were used to characterize the preparednanoemulsion.