Prediction of Lobar Emphysema Progression with a CT-Based Foundational Model

Ariel H. Curiale; Marc Niethammer; Raúl San José Estépar

doi:10.1148/radiol.252958

May 1, 2026RadiologyOpen Access

Prediction of Lobar Emphysema Progression with a CT-Based Foundational Model

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Key Points

This research aims to develop a CT-based model to predict lobar emphysema progression in individuals with chronic obstructive pulmonary disease.
Developed a prognostic model based on chest CT scans.
Evaluated model predictions against observed values in participants with chronic obstructive pulmonary disease.
Model predictions demonstrated strong positive correlations with observed values of lung density decline.

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Implication

Develops a prognostic model for lobar emphysema progression in chronic obstructive pulmonary disease, indicating a new predictive tool.

Abstract

A CT-based prognostic model of lobe density decline and emphysema progression was developed and evaluated in participants with chronic obstructive pulmonary disease at chest CT, and model predictions showed positive correlations with observed values.

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Cite This Study

Curiale et al. (2026) studied this question.

synapsesocial.com/papers/6a17dd123fad632b0f9d9c71 https://doi.org/10.1148/radiol.252958

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Prediction of Lobar Emphysema Progression with a CT-Based Foundational Model

Key Points

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Implication

Abstract

Discussion

Cite This Study

Prediction of Lobar Emphysema Progression with a CT-Based Foundational Model

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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