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May 28, 2026DiabetologiaOpen Access

Clinical and psychological phenotypes of type 1 diabetes and disordered eating derived from a case vignette series: T1DE phenotypes

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Authors

DPDivina PillayKing's College LondonNPNadine PaulKing's College LondonAHAmy HarrisonKing's College London

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Overview

Randomized trial identifies distinct T1DE phenotypes and clinical severity in individuals with type 1 diabetes, suggesting tailored treatment paths.

Key Points

  • This study aims to define and categorize the clinical and psychological phenotypes of type 1 diabetes and disordered eating (T1DE).
  • Developed anonymised case vignettes from baseline assessments of the STEADY and London-T1DE pilot service.
  • Sorted T1DE vignettes into phenotypes and developed a clinical severity grading framework.
  • Analyzed data from 70 participants with detailed biomedical and psychiatric information.
  • Identified three main T1DE phenotypes: insulin-omission (28 participants), restrict T1DE (17), and binge T1DE (25).
  • Categorized clinical severity: 27.1% as low risk, 32.9% moderate risk, and 40.0% severe risk.
  • Over 50% had co-occurring mood disorders, and a significant percentage met criteria for various eating disorders.

Cite This Study

Pillay et al. (2026) studied this question.

synapsesocial.com/papers/6a17de003fad632b0f9da774https://doi.org/10.1007/s00125-026-06756-9
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