Key result
A negative CT pulmonary angiogram safely excluded pulmonary embolism, with 0% of 483 patients experiencing subsequent venous thromboembolism or PE-related death during 3 months of follow-up.
Why the study?
Does a negative CT pulmonary angiogram or negative D-dimer assay safely exclude pulmonary embolism in suspected patients?
Cohort (n=483)
Does a negative CT pulmonary angiogram or negative D-dimer assay safely exclude pulmonary embolism in suspected patients?
A negative single-detector helical CTPA safely excludes pulmonary embolism, and a negative D-dimer assay with low pretest clinical probability makes CTPA unnecessary.
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Supports safe PE exclusion with negative CTPA in suspected cases; leaves open need for randomized confirmation.
Subramaniam et al. (2006) conducted a cohort in Pulmonary embolism (n=483). CT pulmonary angiogram (CTPA) was evaluated on Episodes of venous thromboembolism and mortality. A negative CT pulmonary angiogram safely excluded pulmonary embolism, with 0% of 483 patients experiencing subsequent venous thromboembolism or PE-related death during 3 months of follow-up.
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