May 28, 2002Neurology
Development of daytime somnolence over time in Parkinson’s disease
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Discussion
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Implication
Longitudinal cohort study reveals rising rates of excessive daytime sleepiness in Parkinson’s disease, suggesting ties to cognitive decline and disease progression.
Key Points
- To examine the long-term development, persistence, and progression of excessive daytime sleepiness over a four-year period in patients with Parkinson's disease.
- Longitudinal cohort study evaluating excessive daytime sleepiness (EDS) in 142 patients with Parkinson's disease in 1993.
- Follow-up re-evaluation conducted 4 years later in 1997 to measure persistence, incidence, and clinical correlates of EDS.
- All 11 patients diagnosed with EDS at baseline in 1993 continued to have persistent EDS 4 years later.
- During the 4-year follow-up, 30 patients developed new-onset EDS (annual incidence of 6% per year), raising total EDS prevalence to 29% in 1997.
- The development of EDS correlated significantly with more advanced disease stage and dementia.
Cite This Study
Gjerstad et al. (2002) studied this question.