What question did this study set out to answer?

To assess the prevalence and clinical determinants of sleep disturbances in an unselected community cohort of patients with Parkinson's disease relative to chronic disease and healthy controls.

November 1, 1998Movement Disorders

A community‐based study of sleep disorders in patients with Parkinson's disease

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Authors

ETElise TandbergStavanger University Hospital JLJan LarsenUniversity of Copenhagen KKKaren Karlsen

Discussion

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Implication

Community-based survey finds elevated sleep disorders in Parkinson's disease, highlighting the strong clinical links to depression and levodopa therapy.

Key Points

To assess the prevalence and clinical determinants of sleep disturbances in an unselected community cohort of patients with Parkinson's disease relative to chronic disease and healthy controls.
Conducted a community-based cross-sectional survey evaluating an unselected cohort of 245 patients with Parkinson's disease.
Recruited two age- and sex-matched control groups comprising 100 patients with diabetes mellitus and 100 healthy elderly individuals.
Evaluated sleep architecture disturbances, nocturnal motor symptoms, sedative medication usage, disease duration, and depressive symptoms across cohorts.
Nearly two-thirds (approximately 65%) of patients with Parkinson's disease reported sleep disorders, significantly exceeding rates in diabetes controls (46%) and healthy elderly controls (33%), with one-third rating nocturnal disruption as moderate to severe.
Frequent nighttime awakenings (sleep fragmentation), early awakening, and myoclonic jerks were significantly more prevalent in Parkinson's disease, whereas sleep initiation difficulties did not differ significantly from controls.
Sleep disturbance in Parkinson's disease correlated significantly with depressive symptoms and longer duration of levodopa treatment, alongside significantly higher sedative use compared to healthy controls.

Cite This Study

Tandberg et al. (1998) studied this question.

synapsesocial.com/papers/6a17e9400a2f3f8e1412f0ce https://doi.org/10.1002/mds.870130606

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Implication

Community-based survey finds elevated sleep disorders in Parkinson's disease, highlighting the strong clinical links to depression and levodopa therapy.

A community‐based study of sleep disorders in patients with Parkinson's disease

Discussion

Member takes

Implication

Key Points

Cite This Study

A community‐based study of sleep disorders in patients with Parkinson's disease

Discussion

Member takes

Implication

Key Points

Cite This Study

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