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December 19, 2023Journal of Cancer SurvivorshipOpen Access

Physically demanding jobs linked to ~195% higher risk of reduced employment in male cancer survivors.

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Why the study?

The study was conducted to compare cancer survivors with cancer-free employees regarding employment prospects and the differential impact of working conditions on employment over a 15-year period.

Does cancer diagnosis reduce employment in Norwegian adults?

Population

Cancer survivors and matched cancer-free employees in Norway

Comparison

Cancer survivors vs cancer-free employees across working conditions

Design

Register-based matched cohort study

Follow-up

15-year period

Key result

Male cancer survivors in physically demanding occupations have a significantly increased risk of reduced employment compared to cancer-free peers (interaction HR 2.95).

Authors

GLGiang Huong LeÅHÅsmund HermansenEDEspen Dahl

Discussion

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Overview

Drafting - Clause 2: Research meaning (confirms/challenges/.

Study Design

Type

Cohort (n=262,780)

Structured PICO

Does cancer diagnosis reduce employment in Norwegian adults?

P
Population
262,780 individuals (899 cancer survivors and 261,881 matched cancer-free controls) in Norway, aged 30-50 years.
I
Intervention
Cancer diagnosis (exposure) combined with mechanical and psychosocial working conditions.
C
Comparator
Cancer-free employees matched via nearest-neighbor matching.
O
Outcome
Reduced employment (defined as income from work ≤ 3.5 basic amounts) over a 15-year period.

Main Result

Effect estimate: HR 2.95 (95% CI 1.75-4.95)

p-value: p=<0.001

Male cancer survivors in physically demanding occupations face a significantly higher risk of reduced employment over time, highlighting the need for long-term, occupation-specific support during the return-to-work process.

Limitations

  • Data from Norwegian population limits comparability to other countries.
  • Only included individuals aged 30-50 years old.
  • Propensity score matching may be affected by unobserved confounding variables.
  • Job exposure matrices (JEMs) entail risk of errors in assignments and differential misclassification.
  • Did not differentiate between individuals with one or multiple cancer diagnoses or specific cancer sites and stages.

Cite This Study

Le et al. (2023) conducted a cohort in Cancer (n=262,780). Cancer diagnosis and mechanical job exposure vs. Cancer-free employees was evaluated on Reduced employment (annual income from work ≤ 3.5 basic amounts) (HR 2.95, 95% CI 1.75-4.95, p=<0.001). Male cancer survivors in physically demanding occupations have a significantly increased risk of reduced employment compared to cancer-free peers (interaction HR 2.95).

synapsesocial.com/papers/6a17eb8a40149b897cb475cchttps://doi.org/10.1007/s11764-023-01503-0
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Factors affecting cancer survivors' employment and work ability2007 · 322 citations
  2. 2Employment in a cohort of breast cancer patients2008 · 47 citations
  3. 3Employment status and occupational patterns among working-age US cancer survivors, 2020-2024.2026
  4. 4Long‐term cancer survivors experience work changes after diagnosis: results of a population‐based study2009 · 93 citations
  5. 5Prognostic factors affecting return to work in cancer patients: a systematic review2025