Key result
This review highlights existing heparinization processes, their application in clinical devices, and alternatives to heparinization to reduce the requirement for systemic anticoagulation.
Why the study?
Does surface coating of interventional biomedical devices reduce the need for systemic anticoagulation and prevent device failure?
Population
Patients receiving interventional biomedical devices such as stents, bypass grafts, extracorporeal circuits…
Comparison
Surface coating of medical devices with… vs Systemic anticoagulation
Design
Review
Authors
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May reduce systemic anticoagulation needs via device coatings; leaves open durability and outcome validation.
Does surface coating of interventional biomedical devices reduce the need for systemic anticoagulation and prevent device failure?
Surface coating of medical devices with anticoagulants and alternative agents offers the potential to reduce the need for systemic anticoagulation, though current methods still face challenges with leaching.
Conn et al. (2006) conducted a review in Systemic anticoagulation for interventional biomedical devices. Device surface coating (heparinization and alternatives) vs. Systemic anticoagulation was evaluated. This review highlights existing heparinization processes, their application in clinical devices, and alternatives to heparinization to reduce the requirement for systemic anticoagulation.
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