Synapse
⌘+K
Synapse
PulseExploreClubsResearchersJournals
Instagram
HomeClubsExplore
August 1, 2000Journal of Biological ChemistryOpen Access

Hypoxia Inducible Factor-α Binding and Ubiquitylation by the von Hippel-Lindau Tumor Suppressor Protein

View Full Paper
Ask AI
Bookmark
Share

Authors

MCMatthew E. CockmanThe Francis Crick InstituteNMNorma MassonUniversity of OxfordDMDavid R. MoleAustralian National University

Discussion

Loading...

Member takes

Implication

Key Points

Key points are not available for this paper at this time.

Cite This Study

Cockman et al. (2000) studied this question.

synapsesocial.com/papers/6a1840b0aeefdf6d9c138cc1https://doi.org/10.1074/jbc.m002740200
View Full Paper
Ask AI
Bookmark
Share

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1A second major native von Hippel–Lindau gene product, initiated from an internal translation start site, functions as a tumor suppressor1998 · 232 citations
  2. 2Structure of the VHL-ElonginC-ElonginB Complex: Implications for VHL Tumor Suppressor Function1999 · 871 citations
  3. 3Hypoxia Post-translationally Activates Iron-regulatory Protein 21999 · 149 citations
  4. 4Hypoxia-inducible Factor 1α (HIF-1α) Protein Is Rapidly Degraded by the Ubiquitin-Proteasome System under Normoxic Conditions1997 · 1,681 citations
  5. 5pVHL <sub>19</sub> is a biologically active product of the von Hippel–Lindau gene arising from internal translation initiation1998 · 262 citations