Key result
Increased E/LA strain and decreased LA strain were independently associated with cardiovascular events (HR 1.182) and subsequent stroke (HR 0.844) in patients with persistent atrial fibrillation.
Why the study?
Does echocardiographic assessment of LA strain and E/LA strain predict cardiovascular events and subsequent stroke in patients with persistent atrial fibrillation?
Population
190 patients with persistent atrial fibrillation referred for echocardiographic examinations at a single…
Design
Cohort, Echocardiographic examination was performed by one experienced…
Follow-up
average 29 months
Authors
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May aid event prediction in persistent AF; hypothesis-generating, should not yet change practice.
Cohort (n=190)
Single-blind
No
Does echocardiographic assessment of LA strain and E/LA strain predict cardiovascular events and subsequent stroke in patients with persistent atrial fibrillation?
Effect estimate: HR 1.182 (95% CI 1.086-1.286)
p-value: p=<0.001
E/LA strain and LA strain provide incremental prognostic value over conventional clinical and echocardiographic parameters for predicting cardiovascular events and stroke, respectively, in patients with persistent atrial fibrillation.
Hsu et al. (2016) conducted a cohort in Persistent atrial fibrillation (n=190). E/LA strain and LA strain assessment vs. Conventional clinical and echocardiographic parameters was evaluated on Cardiovascular events (CV mortality, hospitalization for heart failure, myocardial infarction, and stroke) (HR 1.182, 95% CI 1.086-1.286, p=<0.001). Increased E/LA strain and decreased LA strain were independently associated with cardiovascular events (HR 1.182) and subsequent stroke (HR 0.844) in patients with persistent atrial fibrillation.
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