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December 1, 2000Survey of Anesthesiology284 citations

Effects of Controlled-Release Metoprolol on Total Mortality, Hospitalizations, and Well-being in Patients with Heart Failure: The Metoprolol CR/XL Randomized Intervention Trial in Congestive Heart Failure (MERIT-HF)

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ÅHÅke HjalmarsonSFSIDNEY GOLDSTEIN BJÖRN FAGERBERGHWHANS WREDEL

Structured PICO

Does Controlled-Release Metoprolol improve Total Mortality, Hospitalizations, and Well-being in Patients with Heart Failure?

P
Population
Patients with Heart Failure (Congestive Heart Failure)
I
Intervention
Controlled-Release Metoprolol (Metoprolol CR/XL)
O
Outcome
Total Mortality, Hospitalizations, and Well-being

Abstract

HJALMARSON, AKE; FAGERBERG, SIDNEY GOLDSTEIN BJÖRN; WREDEL, HANS; WAAGSTEIN, FINN; KJEKSHUS, JOHN; WIKSTRAND, JOHN; EL ALLAF, DIA; VÍTOVEC, JIRÍ; ALDERSHIVILE, JAN; HALINEN, MATTI; DIETZ, RAINER; NEUHAUS, KARL-LUDWIG; JÁNOSI, ANDRÁS; THORGEIRSSON, GUDMUNDUR; DUNSELMAN, PETER H.J.M.; GULLESTAD, LARS; KUCH, JERZY; HERLITZ, JOHAN; RICKENBACHER, PETER; BALL, STEPHEN; GOTTLIEB, STEPHEN PRAKASH DEEDWANIA FOR THE MERIT-HF STUDY GROUP Author Information

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Hjalmarson et al. (2000) studied this question.

synapsesocial.com/papers/6a18672925af1eb19ec99a00https://doi.org/10.1097/00132586-200012000-00023
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Effects of Controlled-Release Metoprolol on Total Mortality, Hospitalizations, and Well-being in Patients With Heart Failure2000 · 1,402 citations
  2. 2Screening, Endpoint Classification, and Safety Monitoring in the Metoprolol CR/XL Randomised Intervention Trial in Congestive Heart Failure (MERIT-HF)2000 · 9 citations
  3. 3Tolerability of β-Blocker Initiation and Titration in the Metoprolol CR/XL Randomized Intervention Trial in Congestive Heart Failure (MERIT-HF)2002 · 92 citations
  4. 4Metoprolol CR/XL in Female Patients With Heart Failure2002 · 231 citations
  5. 5The large‐scale placebo‐controlled beta‐blocker studies in systolic heart failure revisited: results from CIBIS ‐ II , COPERNICUS and SENIORS ‐ SHF compared with stratified subsets from MERIT ‐ HF2013 · 40 citations