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October 21, 2019MedicinaOpen Access

Left Atrial Function after Atrial Fibrillation Cryoablation Concomitant to Minimally Invasive Mitral Valve Repair: A Pilot Study on Long-Term Results and Clinical Implications

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Key result

AF cryoablation with minimally invasive mitral valve repair achieved 71.4% sinus rhythm at 3.8 years, with better LA volume in SR vs AF relapse patients (60.6 vs 76.8 mL/mq; p=0.008).

Why the study?

The study was designed to explore, by thorough echocardiographic assessment, long-term morphological and functional left atrial outcomes after surgical AF cryoablation concomitant to minimally invasive mitral valve repair.

Does minimally invasive mitral valve repair with concomitant surgical AF cryoablation improve long-term morphological and functional left atrial outcomes in patients maintaining sinus rhythm?

Population

48 patients who underwent minimally invasive mitral valve repair and concomitant surgical AF cryoablation

Design

Pilot study

Follow-up

3.8 ± 2.2 years

Authors

MAMatteo AnselminoCRChiara RoveraGMGiovanni Marchetto

Discussion

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Member takes

Overview

May support concomitant cryoablation in mitral repair for SR; leaves open whether LA remodeling is causal or rhythm-mediated.

Study Design

Type

Cohort (n=48)

Structured PICO

Does minimally invasive mitral valve repair with concomitant surgical AF cryoablation improve long-term morphological and functional left atrial outcomes in patients maintaining sinus rhythm?

P
Population
48 patients undergoing minimally invasive mitral valve repair and concomitant surgical atrial fibrillation cryoablation
I
Intervention
Minimally invasive mitral valve repair with concomitant surgical atrial fibrillation cryoablation
O
Outcome
Long-term morphological and functional left atrial (LA) outcomes (maximal LA volume indexed to body surface area and total LA emptying fraction)surrogate

Main Result

p-value: p=0.008 and 0.015

Concomitant AF cryoablation during minimally invasive mitral valve repair provides high rates of sinus rhythm maintenance, which is associated with improved long-term left atrial morphology and function.

Cite This Study

Anselmino et al. (2019) conducted a cohort in Atrial fibrillation and mitral valve disease (n=48). Minimally invasive mitral valve repair and concomitant surgical AF cryoablation was evaluated on Maximal LA volume indexed to body surface area and total LA emptying fraction (p=0.008 and 0.015). AF cryoablation with minimally invasive mitral valve repair achieved 71.4% sinus rhythm at 3.8 years, with better LA volume in SR vs AF relapse patients (60.6 vs 76.8 mL/mq; p=0.008).

synapsesocial.com/papers/6a189724985da83d549186f3https://doi.org/10.3390/medicina55100709
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Also Consider

Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Limited left atrial surgical ablation effectively treats atrial fibrillation but decreases left atrial function2016 · 12 citations
  2. 2Computational fluid dynamics modelling of left valvular heart diseases during atrial fibrillation2016 · 20 citations
  3. 3Echocardiographic Evaluation of Left Atrial Mechanics: Function, History, Novel Techniques, Advantages, and Pitfalls2015 · 52 citations