Key result
Intraoperative cooled-tip radiofrequency ablation for atrial fibrillation produced coagulation necrosis up to 5.5 mm deep, but transmurality was achieved in only 75% of lesions.
Why the study?
What are the histopathological characteristics and transmurality of intraoperatively induced linear radiofrequency ablation lesions in patients with chronic atrial fibrillation?
Observational (n=7)
What are the histopathological characteristics and transmurality of intraoperatively induced linear radiofrequency ablation lesions in patients with chronic atrial fibrillation?
Intraoperative cooled-tip RF ablation for AF produces coagulation necrosis up to 5.5 mm, but a significant proportion of lesions, particularly in the left atrial isthmus, are non-transmural.
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Incomplete transmurality may limit surgical AF ablation efficacy; leaves open optimal lesion parameters in chronic AF.
Deneke et al. (2005) conducted an observational in chronic atrial fibrillation (n=7). intraoperative cooled-tip radiofrequency ablation was evaluated on Transmurality of ablation lesions. Intraoperative cooled-tip radiofrequency ablation for atrial fibrillation produced coagulation necrosis up to 5.5 mm deep, but transmurality was achieved in only 75% of lesions.