Why the study?
Does wide local excision improve prognosis and reduce recurrence compared to marginal or simple excision in patients with well-differentiated liposarcoma?
Population
58 patients with well-differentiated liposarcomas treated at the Mayo Clinic
Comparison
Surgical excision (wide local excision) vs Marginal or simple excision
Design
Case_series
Follow-up
average 9.3 years
Authors
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May support wide excision for extremity tumors; case-report data leave open need for prospective validation.
Does wide local excision improve prognosis and reduce recurrence compared to marginal or simple excision in patients with well-differentiated liposarcoma?
Extremity well-differentiated liposarcomas have a better prognosis than retroperitoneal or scrotal tumors, and wide local excision significantly reduces recurrence rates compared to marginal or simple excision.
Lucas et al. (1994) studied this question.
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