Evolutionary adaptation in fucosyllactose uptake systems supports bifidobacteria-infant symbiosis

Mikiyasu Sakanaka; Morten Ejby; Aina Gotoh; Toshihiko Katoh; Keisuke Yoshida; Toshitaka Odamaki; Hiroyuki Yachi; Yuta Sugiyama; Shin Kurihara; Junko Hirose; Tadasu Urashima; Jin‐zhong Xiao; Motomitsu Kitaoka; Satoru Fukiya; Atsushi Yokota; Leila Lo Leggio; Maher Abou Hachem; Takane Katayama

doi:10.1126/sciadv.aaw7696

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Abstract

to HMOs, in which the gain-of-function mutations enable FL transporter-2 to efficiently capture major fucosylated HMOs. Our results provide a molecular insight into HMO-mediated symbiosis and coevolution between bifidobacteria and humans.

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Sakanaka et al. (2019) studied this question.

synapsesocial.com/papers/6a18a7980b0ae5b64a919ec8 https://doi.org/10.1126/sciadv.aaw7696

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Evolutionary adaptation in fucosyllactose uptake systems supports bifidobacteria-infant symbiosis

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Abstract

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Evolutionary adaptation in fucosyllactose uptake systems supports bifidobacteria-infant symbiosis

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Abstract

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