Key result
The novel tubulin-associated RING/B-box protein MURF2 acts as a transient adaptor between microtubules, titin, and nascent myosin filaments during muscle sarcomere assembly.
Authors
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Hypothesis-generating for sarcomere-related myopathies; extends transient adaptor models but requires in vivo validation before clinical consideration.
Pizon et al. (2002) studied Muscle sarcomere assembly. MURF2 protein was evaluated. The novel tubulin-associated RING/B-box protein MURF2 acts as a transient adaptor between microtubules, titin, and nascent myosin filaments during muscle sarcomere assembly.
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