Key result
Pericardial adipose tissue was positively associated with the presence of coronary artery calcification in African Americans (P<0.001), but not in European Americans (P=0.68).
Why the study?
Are measures of adiposity associated with subclinical atherosclerosis in African Americans and European Americans with type 2 diabetes?
Population
1,315 patients with type 2 diabetes (753 African Americans and 562 European Americans)
Design
Cross-sectional
Authors
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Ethnic-specific pericardial fat-CAC links in T2D merit prospective confirmation; does not yet support ancestry-based risk stratification.
Cross-Sectional (n=1,315)
Are measures of adiposity associated with subclinical atherosclerosis in African Americans and European Americans with type 2 diabetes?
p-value: p=<0.001
Pericardial adipose tissue is positively associated with coronary artery calcification in African Americans with type 2 diabetes, highlighting ethnic-specific differences in adiposity and cardiovascular risk.
Yuan et al. (2016) conducted a cross-sectional in Type 2 diabetes (n=1,315). Measures of adiposity (BMI, WC, PAT, VAT, SAT) vs. European Americans vs African Americans was evaluated on Calcified plaque in coronary arteries, carotid arteries, and aorta (p=<0.001). Pericardial adipose tissue was positively associated with the presence of coronary artery calcification in African Americans (P<0.001), but not in European Americans (P=0.68).
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