Key result
A 1-SD increment in depressive symptom score was associated with increased heart rate (mean difference 0.5; 95% CI 0.2-0.7) and reduced heart rate variability (RMSSD -0.8, SDNN -0.7).
Why the study?
Are psychosocial factors associated with heart rate and its short-term variability in a multi-ethnic cohort of adults aged 45 to 84 years?
Population
6814 men and women aged 45 to 84 years taking part in the first examination of the Multi-Ethnic Study of…
Design
Cross-sectional
Authors
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Hypothesis-generating for autonomic effects of depressive symptoms; prospective studies needed before clinical implications in diverse adults.
Cross-Sectional (n=6,814)
Are psychosocial factors associated with heart rate and its short-term variability in a multi-ethnic cohort of adults aged 45 to 84 years?
Effect estimate: Mean difference 0.5 for HR (95% CI 0.2-0.7)
Higher depressive symptom scores are associated with increased heart rate and reduced short-term heart rate variability, which are markers of increased cardiovascular risk.
Ohira et al. (2008) conducted a cross-sectional in Cardiovascular risk (n=6,814). Depressive symptom score was evaluated on Mean values of heart rate (HR) and its short-term variability (SDNN and RMSSD) (Mean difference 0.5 for HR, 95% CI 0.2-0.7). A 1-SD increment in depressive symptom score was associated with increased heart rate (mean difference 0.5; 95% CI 0.2-0.7) and reduced heart rate variability (RMSSD -0.8, SDNN -0.7).
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