Key result
Enterovirus-D68 infection primarily causes respiratory disease but can disseminate systemically and invade the central nervous system, leading to severe complications such as acute flaccid myelitis.
Why the study?
Knowledge gaps remain regarding the mechanisms of systemic dissemination, CNS entry, induction of AFM or other CNS complications, and the role of virus and host factors in EV-D68 pathogenesis.
Answers are grounded in this paper and cite their sources.
This review highlights the knowledge gaps on the mechanisms of systemic dissemination, routes of entry into the CNS, and the role of virus and host factors in the pathogenesis of EV-D68.
studies. This review highlights the knowledge gaps on the mechanisms of systemic dissemination, routes of entry into the CNS and mechanisms to induce AFM or other CNS complications, as well as the role of virus and host factors in the pathogenesis of EV-D68.
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Ayudhya et al. (2021) conducted a review in Enterovirus-D68 infection. Enterovirus-D68 was evaluated. Enterovirus-D68 infection primarily causes respiratory disease but can disseminate systemically and invade the central nervous system, leading to severe complications such as acute flaccid myelitis.
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