Key result
Severe cardiac Raynaud's phenomenon independently predicted the development of systolic left ventricular dysfunction, which occurred in 5 of 51 systemic sclerosis patients over 7.1 years.
Why the study?
Does severe cardiac Raynaud's phenomenon predict long-term systolic LV dysfunction in patients with systemic sclerosis?
Cohort (n=51)
Does severe cardiac Raynaud's phenomenon predict long-term systolic LV dysfunction in patients with systemic sclerosis?
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Severe cardiac Raynaud's phenomenon is a strong long-term predictor of systolic LV dysfunction in systemic sclerosis patients, identifying those at high risk of cardiac deterioration.
Mizuno et al. (2010) conducted a cohort in Systemic sclerosis (n=51). Severe cardiac Raynaud's phenomenon (cold-induced reversible myocardial ischaemia) was evaluated on Development of systolic left ventricular dysfunction (LVEF <50%). Severe cardiac Raynaud's phenomenon independently predicted the development of systolic left ventricular dysfunction, which occurred in 5 of 51 systemic sclerosis patients over 7.1 years.
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