Why the study?
Does systemic sclerosis impair systolic left ventricular function compared to matched controls?
Population
30 consecutive patients with systemic sclerosis and 48 controls matched for age and sex.
Comparison
Non-invasive cardiac assessment including… vs Age- and sex-matched healthy controls.
Design
Case-control
Authors
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Systemic sclerosis may associate with subclinical LV systolic impairment; Level 4 case-control data leave open screening implications.
Does systemic sclerosis impair systolic left ventricular function compared to matched controls?
Systemic sclerosis is frequently associated with impaired systolic left ventricular function, which can be detected by non-invasive methods such as echocardiography and systolic time intervals even in the absence of LV cavity dilatation.
Kazzam et al. (1991) studied this question.
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