Why the study?
Does Doppler echocardiography detect abnormal ventricular diastolic filling in patients with systemic sclerosis?
Population
51 consecutive patients with systemic sclerosis
Design
Cross-sectional
Authors
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Diastolic abnormalities may signal early myocardial involvement in systemic sclerosis; hypothesis-generating and requires prospective validation before screening use.
Does Doppler echocardiography detect abnormal ventricular diastolic filling in patients with systemic sclerosis?
Diastolic abnormalities detected by Doppler echocardiography may represent early, isolated evidence of myocardial fibrosis in systemic sclerosis patients prior to clinically evident myocardial disease.
Maione et al. (2008) studied this question.
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