In a prospective study of 41 persons with ocular hypertension followed for 20 years, 14 individuals (34 per cent) developed glaucoma. Of 38 persons who 20 years ago were normotensive, 2 (5 per cent), developed glaucoma. This difference is significant. The mean IOP of the remaining untreated ocular hypertensives was about 7 mmHg higher than the mean tension in the control group.
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Lundberg et al. (1987) studied this question.
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