Key result
Absolute stress myocardial blood flow alone was superior to myocardial flow reserve for detecting hemodynamically significant coronary artery disease (AUC 0.94 vs. 0.90, P=0.02).
Why the study?
Does absolute stress myocardial blood flow alone improve the detection of significant coronary artery disease compared to myocardial flow reserve in patients with moderate pre-test likelihood of CAD?
Observational (n=104)
Does absolute stress myocardial blood flow alone improve the detection of significant coronary artery disease compared to myocardial flow reserve in patients with moderate pre-test likelihood of CAD?
Effect estimate: AUC
Absolute Event Rate: 0.94% vs 0.9%
p-value: p=0.02
Absolute stress myocardial blood flow alone is superior to myocardial flow reserve for detecting hemodynamically significant CAD, potentially allowing for shorter imaging protocols and lower radiation doses.
Authors
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May support shorter PET protocols for CAD detection; leaves open prospective outcome validation.
Joutsiniemi et al. (2014) conducted an observational in Coronary artery disease (n=104). Absolute stress myocardial blood flow (MBF) vs. Myocardial flow reserve was evaluated on Detection of significant coronary stenosis (AUC, p=0.02). Absolute stress myocardial blood flow alone was superior to myocardial flow reserve for detecting hemodynamically significant coronary artery disease (AUC 0.94 vs. 0.90, P=0.02).