Key result
The subendocardial viability index was strongly determined by the diastolic/systolic time ratio (r2=0.81) and left ventricular end-diastolic pressure, whereas aortic pressure did not contribute.
Why the study?
What are the haemodynamic determinants of the subendocardial viability index (SVI) and how does neglecting LVEDP affect its non-invasive estimation?
Population
38 subjects, mean age 47 +/- 14 years, including 9 controls and 29 patients with various cardiac diseases.
Comparison
Invasive measurement of high-fidelity pressures… vs SVI calculated assuming zero LVEDP.
Design
Cross-sectional
Authors
Loading...
Noninvasive SVI estimation neglecting LVEDP may overestimate values with high filling pressures; hypothesis-generating, needs prospective validation.
Observational (n=38)
What are the haemodynamic determinants of the subendocardial viability index (SVI) and how does neglecting LVEDP affect its non-invasive estimation?
Effect estimate: r2 0.81
Non-invasive estimation of the subendocardial viability index should incorporate LVEDP, as neglecting it significantly overestimates SVI in patients with elevated left ventricular filling pressures.
Chemla et al. (2008) conducted an observational in Various cardiac diseases (n=38). Invasive haemodynamic measurement was evaluated on Haemodynamic correlates of the subendocardial viability index (SVI) (r2 0.81). The subendocardial viability index was strongly determined by the diastolic/systolic time ratio (r2=0.81) and left ventricular end-diastolic pressure, whereas aortic pressure did not contribute.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: