Key result
Cardiac magnetic resonance imaging effectively identifies left ventricular dysfunction, adverse remodeling, reduced stress-response, and elevated native T1 relaxation times in patients with chronic kidney disease.
Why the study?
Does cardiac magnetic resonance (CMR) imaging effectively characterize cardiac involvement in patients with chronic kidney disease?
Systematic Review
Does cardiac magnetic resonance (CMR) imaging effectively characterize cardiac involvement in patients with chronic kidney disease?
CMR provides detailed multiparametric characterization of uremic cardiomyopathy, including early detection of fibrosis and subclinical dysfunction, in patients with chronic kidney disease.
PURPOSE OF REVIEW: The aim of the review was to identify and describe recent advances (over the last 3 years) in cardiac magnetic resonance (CMR) imaging in patients with chronic kidney disease (CKD). We conducted a literature review in line with current guidelines. RECENT FINDINGS: The authors identified 22 studies. Patients with CKD had left ventricular global and regional dysfunction and adverse remodeling. Stress testing with CMR revealed a reduced stress-response in CKD patients. Native T1 relaxation times (as a surrogate markers of fibrosis) are elevated in CKD patients, proportional to disease duration. Patients with CKD have reduced strain magnitudes and reduced aortic distensibility. SUMMARY: CMR has diagnostic utility to identify and characterize cardiac involvement in this patient group. A number of papers have described novel findings over the last 3 years, suggesting that CMR has potential to become more widely used in studies in this patient group.
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Mangion et al. (2018) conducted a systematic review in Chronic kidney disease. Cardiac magnetic resonance (CMR) was evaluated. Cardiac magnetic resonance imaging effectively identifies left ventricular dysfunction, adverse remodeling, reduced stress-response, and elevated native T1 relaxation times in patients with chronic kidney disease.
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