What question did this study set out to answer?

To assess and compare the identification and success rates of different two-step targeted axillary dissection techniques following neoadjuvant chemotherapy in breast cancer.

July 3, 2023Annals of Surgical OncologyOpen Access

Comparing Methods for Targeted Axillary Dissection in Breast Cancer Patients: A Nationwide, Retrospective Study

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Authors

FMFrederikke MunckGentofte Hospital PJPernille JepsenZealand University Hospital PZPernille ZeuthenLillebaelt Hospital

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Implication

Retrospective cohort study reveals high failure rates in two-step targeted axillary dissection for breast cancer, indicating iodine seeds outperform ink marking.

Key Points

To assess and compare the identification and success rates of different two-step targeted axillary dissection techniques following neoadjuvant chemotherapy in breast cancer.
Retrospective nationwide cohort study of 543 patients undergoing two-step targeted axillary dissection in Denmark between January 2016 and August 2021.
Identified patients through the Danish Breast Cancer Group database and medical files to evaluate coil marking at diagnosis followed by preoperative localization with hook-wires, iodine seeds, or skin ink.
Preoperative ultrasound-guided re-marking was achievable in 79.4% of patients, with nonidentification of the marked node significantly more likely in patients achieving axillary pathological complete response.
Secondary localization with iodine seeds was significantly more successful than ink marking (OR 5.34, 95% CI 1.62–17.60).
Among successfully re-marked patients, the marked lymph node identification rate was 91%, the sentinel node identification rate was 95%, and the complete targeted axillary dissection success rate was 82.3%.

Cite This Study

Munck et al. (2023) studied this question.

synapsesocial.com/papers/6a1903da4dd69184e54f76b1 https://doi.org/10.1245/s10434-023-13792-x

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Implication

Retrospective cohort study reveals high failure rates in two-step targeted axillary dissection for breast cancer, indicating iodine seeds outperform ink marking.

Comparing Methods for Targeted Axillary Dissection in Breast Cancer Patients: A Nationwide, Retrospective Study

Discussion

Member takes

Implication

Key Points

Cite This Study

Comparing Methods for Targeted Axillary Dissection in Breast Cancer Patients: A Nationwide, Retrospective Study

Discussion

Member takes

Implication

Key Points

Cite This Study

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