Key result
4D flow CMR reliably quantifies LV kinetic energy with ~6% variability across studies.
Why the study?
There is emerging evidence supporting the potential clinical value of LV intracavity blood flow kinetic energy assessment using 4D flow CMR, but studies on its quantification methods and clinical significance needed summarization.
Does 4D flow CMR assessment of LV blood flow kinetic energy provide clinically relevant and reproducible hemodynamic information in patients with cardiovascular diseases?
Systematic Review (n=16)
Does 4D flow CMR assessment of LV blood flow kinetic energy provide clinically relevant and reproducible hemodynamic information in patients with cardiovascular diseases?
4D flow CMR assessment of LV blood flow kinetic energy is a highly reproducible, emerging imaging biomarker with potential clinical utility for evaluating LV hemodynamics in various cardiovascular diseases.
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High reproducibility may support clinical adoption of 4D flow CMR for LV hemodynamics; extends evidence for diastolic function assessment.
Kaur et al. (2020) conducted a systematic review in Cardiovascular diseases (LV diastolic function, heart failure, ischemic heart disease, valvular heart disease) (n=16). 4D flow cardiovascular magnetic resonance (CMR) for LV blood flow kinetic energy assessment was evaluated on Reproducibility of LV blood flow kinetic energy hemodynamic assessment. Left ventricular blood flow kinetic energy assessment by 4D flow CMR is a highly reproducible method (mean coefficient of variability 6 ± 2%) that shows great promise for evaluating LV hemodynamics.
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