Key result
Among older African Americans, increases in lifetime discrimination burden and racial discrimination were associated with increases in white matter lesion volume (ps < .03).
Why the study?
The study was designed to explore interactive relations of lifetime discrimination burden, racial discrimination, and age with MRI-assessed white matter lesion volume among African Americans.
Is lifetime discrimination burden and racial discrimination associated with increased white matter lesion volume in African Americans?
Observational (n=71)
Is lifetime discrimination burden and racial discrimination associated with increased white matter lesion volume in African Americans?
Effect estimate: B = 0.05 (lifetime discrimination); B = 0.03 (racial discrimination)
p-value: p = 0.014 (lifetime); p = 0.001 (racial)
Among older African Americans, increased lifetime and racial discrimination burden is associated with greater subclinical cerebrovascular disease as measured by white matter lesion volume.
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May signal higher cerebrovascular risk in older African Americans; extends observational data but leaves causal effects open.
Moody et al. (2018) conducted an observational in Subclinical cerebrovascular disease (n=71). Lifetime discrimination burden and racial discrimination was evaluated on MRI-assessed white matter lesion volume (WMLV) (B = 0.05 (lifetime discrimination); B = 0.03 (racial discrimination), p=p = 0.014 (lifetime); p = 0.001 (racial)). Among older African Americans, increases in lifetime discrimination burden and racial discrimination were associated with increases in white matter lesion volume (ps < .03).