Key result
Current smoking was significantly associated with higher serum IL-6 levels compared to former smoking, particularly in males, while CRP levels showed no association with smoking intensity.
Why the study?
Does current smoking increase circulating levels of CRP and IL-6 compared to former smoking in heavy smokers?
Population
154 current and former smokers between 40 and 80 years of age with 25 or more pack-years of smoking history
Comparison
Current smoking vs Former smoking
Design
Cross-sectional
Authors
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Current smoking links to higher IL-6 but not CRP in heavy smokers; hypothesis-generating without supporting practice change.
RCT (n=154)
Does current smoking increase circulating levels of CRP and IL-6 compared to former smoking in heavy smokers?
IL-6 levels, but not CRP levels, are significantly associated with smoking status and intensity in heavy smokers.
Aldaham et al. (2015) conducted an RCT in Current and former heavy smokers (n=154). Current smoking vs. Former smoking was evaluated on Inflammatory markers (CRP and IL-6) levels. Current smoking was significantly associated with higher serum IL-6 levels compared to former smoking, particularly in males, while CRP levels showed no association with smoking intensity.
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