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May 29, 2026JAMA Surgery

Mesh Placement and Risk of Recurrence and Bowel Obstruction After Primary Ventral Hernia Repair

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Authors

EGEvy Á Lakjuni GuttesenHRHugin ReistrupAJAndrea Joensen

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Overview

Cohort study compares risks of reoperation for recurrence and bowel obstruction by mesh placement technique, indicating onlay as a safer option.

Key Points

  • This research aims to compare the risk of reoperation due to recurrence and bowel obstruction across different mesh placements in ventral hernia repair.
  • Danish nationwide register-based cohort study including adults aged ≥18 years.
  • Participants underwent elective primary hernia repair with various mesh placement techniques.
  • Data analyzed from national patient registers and databases, with follow-up until November 1, 2025.
  • Retromuscular mesh placement increases reoperation risk for recurrence (HR, 1.63; 95% CI, 1.12-2.38).
  • IPOM placement also shows higher recurrence risk compared to onlay (HR, 1.38; 95% CI, 1.02-1.86).
  • Bowel obstruction risk is significantly increased after retromuscular (HR, 2.01; 95% CI, 1.05-3.82) and IPOM (HR, 3.47; 95% CI, 2.27-5.28) mesh placements compared to onlay.

Cite This Study

Guttesen et al. (2026) studied this question.

synapsesocial.com/papers/6a192c0ffab5b468c4414f9dhttps://doi.org/10.1001/jamasurg.2026.1626
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Mesh placement and patient-reported outcomes in primary ventral hernia repair: a nationwide survey- and register-based study2026
  2. 2Association Between Mesh Placement and Recurrence and Chronic Pain After Incisional Hernia Repair: A Systematic Review and Network Meta‐Analysis2026
  3. 3THE IMPORTANCE OF HORIZONTAL MESH OVERLAP IN OPEN RETROMUSCULAR MIDLINE INCISIONAL HERNIA REPAIR: NATIONWIDE ANALYSIS WITH LONG-TERM FOLLOW-UP2024
  4. 4Outcomes after ventral mesh removal: a multicentric cohort study2026
  5. 5Long-Term Recurrence and the Safety of Mesh Use After Emergency Ventral Hernia Repair2025