Bio-Manguinhos and new generation of vaccines: consolidation of mRNA-LNP production and evaluation of critical quality attributes at pilot scale

Daniele Rocha; Elaine Costa; Sthefanie Ribeiro; Raphaela Barbosa; Karoline Alves; Gabriela Chemp; Anderson Martins; João Benvindo; Elaine Teles; Maria Gonçalves

doi:10.35259/isi.2026_76327

January 1, 2026Open Access

Bio-Manguinhos and new generation of vaccines: consolidation of mRNA-LNP production and evaluation of critical quality attributes at pilot scale

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Key Points

The aim is to evaluate the production and critical quality attributes of mRNA-based vaccines at a pilot scale.
Pilot-scale production of mRNA-lipid nanoparticle (LNP) vaccines
Assessment of critical quality attributes during production
Participation in the International Symposium on Immunobiologicals
Successful consolidation of mRNA-LNP production processes
Improvement in the evaluation of vaccine quality attributes
Presentation aligns with current advancements in vaccine technology

Implication

Presentation discusses mRNA-LNP vaccine production quality in pilot scale by Bio-Manguinhos, indicating significant advancements.

Abstract

Os autores externos submeteram sua publicação para apresentação de trabalho no evento 'International Symposium on Immunobiologicals', que foi coordenado e organizado pelo Instituto de Tecnologia em Imunobiológicos (Bio-Manguinhos), da Fundação Oswaldo Cruz.

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Cite This Study

Rocha et al. (2026) studied this question.

synapsesocial.com/papers/6a192c0ffab5b468c4415146 https://doi.org/10.35259/isi.2026_76327

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Bio-Manguinhos and new generation of vaccines: consolidation of mRNA-LNP production and evaluation of critical quality attributes at pilot scale

Key Points

Implication

Abstract

Discussion

Cite This Study

Bio-Manguinhos and new generation of vaccines: consolidation of mRNA-LNP production and evaluation of critical quality attributes at pilot scale

Key Points

Implication

Abstract

Discussion

Cite This Study

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