Key result
CMR reveals delayed contrast enhancement in 100% of pediatric myocarditis cases.
Observational (n=7)
No
Cardiac MRI effectively identifies key structural changes such as myocardial edema and delayed contrast enhancement in children with myocarditis.
Suggests CMR role in pediatric myocarditis assessment; hypothesis-generating and should not yet change practice.
Background: There is a need for the systematization, generalization and analysis of the structural changes of the myocardium, occurring in patients with myocarditis. This disease is rare; therefore, structured information in the field of radiological diagnostics is still insufficient within national publications. Aim: The study purpose was to determine the significance and specificity of changes observed in cardiac magnetic resonance images in patients with myocarditis, and to compare the obtained results with the literature data. Methods: 7 patients, including children aged 4 and 6, with a verified diagnosis of myocarditis were retrospectively examined. Results: The analysis of the obtained images revealed the most common changes related to myocarditis, such as myocardial edema, impaired myocardial contractility, increased delayed accumulation of the contrast agent. The pathophysiological mechanisms of the found structural changes were analyzed and described. Conclusion: Magnetic resonance imaging is the most important non-invasive method for diagnosing myocarditis, which allows one to identify the lesion of the heart muscle, to assess the extent of its damage, to differentiate myocarditis from other diseases, as well as to assess the dynamics when evaluating the effectiveness of therapy.
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Fomina et al. (2023) conducted an observational in Myocarditis (n=7). Cardiac Magnetic Resonance Imaging (MRI) was evaluated on MRI findings (myocardial edema, impaired contractility, delayed contrast enhancement). Cardiac magnetic resonance imaging in children with myocarditis revealed delayed contrast enhancement in 100%, myocardial edema in 57%, and impaired contractility in 42% of cases.
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