Indium 111-monoclonal antimyosin antibody imaging in the diagnosis of acute myocarditis.
Why the study?
Does Indium 111-monoclonal antimyosin antibody imaging accurately detect acute myocarditis compared to right ventricular biopsy in suspected patients?
Population
28 patients clinically suspected of having myocarditis, 25 of whom had left ventricular ejection fractions…
Comparison
Indium 111-monoclonal antimyosin antibody imaging vs Right ventricular biopsy performed within 48…
Design
Cross-sectional
Authors
Discussion
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Member takes
Implication
May aid sensitive screening for myocarditis; leaves open prospective validation before guiding biopsy decisions.
Structured PICO
Does Indium 111-monoclonal antimyosin antibody imaging accurately detect acute myocarditis compared to right ventricular biopsy in suspected patients?
P
Population
28 patients clinically suspected of having myocarditis, 25 of whom had left ventricular ejection fractions of less than 45%
I
Intervention
Indium 111-monoclonal antimyosin antibody imaging
C
Comparator
Right ventricular biopsy performed within 48 hours of the scan
O
Outcome
Diagnostic accuracy (sensitivity and specificity) for acute myocarditissurrogate
Indium 111-monoclonal antimyosin antibody imaging is a highly sensitive screening tool for acute myocarditis, useful for identifying patients who require a confirmatory right ventricular biopsy.
Cite This Study
Yasuda et al. (1987) studied this question.