Randomized trial explores oncologic outcomes of organ preservation in rectal cancer, implying effective strategies for selected patients.
Key Points
This research aims to evaluate long-term oncologic outcomes of transanal endoscopic microsurgery following neoadjuvant chemoradiotherapy in rectal cancer patients.
Identified 92 patients from a rectal cancer database who underwent TEM after neoadjuvant CRT between January 2005 and October 2019.
Reviewed demographic data, follow-up intervals, and oncologic outcomes for analysis.
Calculated recurrence rates based on pathologic response and tumor stage.
7.6% of patients developed local recurrence and 6.5% developed systemic metastases during a mean follow-up of 57.5 months.
Patients with complete pathologic response (ypT0) showed local recurrence and distant metastasis rates of 4% and 2%, respectively.
Higher-stage patients had significantly increased rates of local and distant failure, particularly stage III.