Serum Level of Calprotectin and High Sensitive C-Reactive Protein in Patients with Psoriatic Arthritis and Their Relation to The Severity of the Disease

February 1, 2025Open Access

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Key Points

To examine serum calprotectin and hs-CRP levels in psoriatic arthritis and their correlation with disease severity.
55 psoriatic arthritis cases and 30 healthy controls were assessed.
Participants underwent medical history, musculoskeletal examination, ultrasound of joints, and laboratory tests.
Receiver operating characteristic analysis determined optimal cut-off values for calprotectin and hs-CRP.
Serum calprotectin and hs-CRP levels were significantly elevated in PsA cases (p<0.05).
Both biomarkers positively correlated with PASI, DAPSA-28, and ultrasound scores.
Optimal cut-off values were identified as >144 ng/ml for calprotectin and >1.63 mg/L for hs-CRP.

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Assesses inflammatory markers in psoriatic arthritis, suggesting enhanced disease monitoring.

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Elbiely et al. (2025) studied this question.

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