Compares behavioural effects of five antidepressants in animal models of depression, suggesting more efficient screening methods.
Antidepressants were compared for their behavioural effects in some animal models of depression. The results were interpreted for a better insight into the underlying mechanisms as well as for a rank ordering of the models. It is concluded that the model of depression involving inescapable foot shock, if considered together with the forced swimming test or the tail suspension test, can more efficiently screen putative antidepressants.
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PAL et al. (1993) studied this question.
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