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Synapse
May 29, 2026Open Access

Role of Transthoracic Ultrasound in Predicting Weaning and Successful Extubating from Mechanical Ventilation in Neonatal Intensive Care Unit

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Authors

MAMarwa AbdelrazicRMReham MokhtarAAAhmed Ahmed

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Overview

Prospective cross-sectional study demonstrates weaning prediction in neonates using transthoracic ultrasound, indicating clinical relevance.

Key Points

  • This study aims to evaluate the effectiveness of transthoracic ultrasound in predicting successful extubation and weaning from mechanical ventilation in neonates.
  • Prospective cross-sectional study including 40 neonates on mechanical ventilation in a NICU.
  • Assessment of diaphragmatic thickening fraction (DTF), IVC diameter, cardiac contractility, and rapid shallow breathing index (RSBI) during spontaneous breathing trials.
  • Comparison of diaphragmatic thickness at inspiration and expiration between successful and failed weaning cases.
  • Neonates who failed weaning had significantly lower diaphragmatic thickness at inspiration (DTI) of 1.69±0.07 mm compared to those who succeeded (1.9±0.10 mm, p<0.001).
  • Diaphragmatic thickness at expiration (DTE) was slightly lower in failed cases (1.46±0.08 mm) than in successful ones (1.49±0.06 mm), with no significant difference (p=0.31).
  • Failed cases also demonstrated lower DTF and smaller IVC diameter alongside reduced contractility.

Cite This Study

Abdelrazic et al. (2026) studied this question.

synapsesocial.com/papers/6a192e95fab5b468c4417b6fhttps://doi.org/10.21608/anj.2025.386012.1113
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Role of diaphragmatic ultrasound in predicting weaning success from mechanical ventilation in pediatric intensive care unit2024 · 4 citations
  2. 2Diaphragmatic and lung ultrasound as predictors of weaning outcomes of mechanically ventilated patients2026
  3. 3The impact of heart, lung and diaphragmatic ultrasound on prediction of failed extubation from mechanical ventilation in critically ill patients.2024
  4. 4Diaphragm ultrasound parameters and rapid shallow breathing index for predicting weaning failure in mechanically ventilated infants: a prospective observational PICU study2026
  5. 5Integrated Multimodal Critical Care Ultrasound for Mechanism-Based Prediction of Weaning Failure: A Prospective Pilot Study2026