Demonstrates efficient C-4 alkylation in pyridines, suggesting a novel synthetic approach.
Herein, we report a metal- and light-free C-4 alkylation of pyridines through a decarboxylative Minisci-type reaction between fumarate-derived pyridinium salts and aryliodine(III) dicarboxylates. In this protocol, an NADH analogue serves...
No takes yet. Share an insight, caveat, or question.
Liang et al. (2026) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: