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May 29, 2026Journal of Clinical Oncology

Standardized mean differences of primary outcomes found in randomized controlled trials of wellness interventions among medical trainees: A systematic review and meta-analysis.

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Authors

AHAndrew I. HearnUniversity of LouisvilleDCDaniella ChrabuszczMercer UniversityJBJames BaoWashington University in St. Louis

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Implication

Systematic review reports little overall effect of wellness interventions in medical trainees, suggesting future research avenues.

Key Points

  • This review aims to assess the efficacy of wellness interventions in medical trainees through a systematic analysis of randomized controlled trials.
  • A comprehensive literature search was conducted across multiple databases from inception until March 2022 for randomized trials.
  • Inclusion criteria focused on wellness measures such as depression, stress, and anxiety in medical trainees.
  • Data extraction was performed from 46 studies, with standardized mean differences calculated for meta-analysis.
  • The pooled effect size for wellness interventions was 0.017, indicating minimal effect, with a 95% confidence interval of -0.501 to 0.536.
  • High heterogeneity among studies was noted, with an I^2 of 0.904, suggesting varied designs and outcomes.
  • No significant beneficial effects were demonstrated for the overall effectiveness of the interventions.

Cite This Study

Hearn et al. (2026) studied this question.

synapsesocial.com/papers/6a192f07fab5b468c44184c2https://doi.org/10.1200/jco.2026.44.16_suppl.9011
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Demographic trends and outcome measures found in randomized controlled trials of wellness interventions among medical trainees: A systematic review.2024
  2. 2The Role of Wellness and Well-being in Addressing Medical Student Burnout in the United States: A Scoping Review2025 · 1 citations
  3. 3Interventions to promote medical student well-being: an overview of systematic reviews2024 · 35 citations
  4. 4Evolving trends in medical trainee wellbeing research from 2014 to 2023: A bibliometric analysis2025
  5. 5Resident Physician Perceptions of Wellness Interventions: A Single-Institution Qualitative Study2026